Intracranial Bleeding Risk from Thrombolytic Therapy of MI

Select Criteria:
Patient 75 years old or older (1 point)
Patient of Black race (1 point)
Patient is female (1 point)
Prior history of stroke (1 point)
Systolic BP >= 160 mmHg (1 point)
Body weight less <= 65 Kg for women, <= 80 Kg for men (1 point)
INR > 4 or prothrombin time > 24 seconds (1 point)
TPA used instead of another thrombolytic (1 point)
Results: Total Criteria Point Count:
Risk of Cerebral Bleeding
0-1 points:0.69% Risk
2 points:1.02% Risk
3 points:1.63% Risk
4 points:2.49% Risk
5-8 points:4.11% Risk
  1. Brass LM, Lichtman JH, Wang Y, et al. Intracranial hemorrhage associated with thrombolytic therapy for elderly patients with acute myocardial infarction. Stroke. 2000; 31: 1802-11.
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