Close
New

Medscape is available in 5 Language Editions – Choose your Edition here.

Myelodysplastic Syndrome International Prognostic Scoring System

Select Criteria:
Percentage of Bone Marrow Blasts
< 5 percent (0 points)
5 to 10 percent (0.5 points)
11 to 20 percent (1.5 points)
21 to 30 percent (2.0 points)
Karyotype
Normal, Y-, 5q-, 20q- (0 points)
Abnormal chromosome 7 or 3 or more abnormalities (1.0 points)
All other cytogenic abnormalities (0.5 points)
Cytopenias (defined as hemoglobin < 10 g/dL, absolute neutrophil count < 1800/microL, platelet count < 100,000/microL)
No cytopenia or cytopenia of 1 cell type (0 points)
Cytopenia of 2 or 3 cell types (0.5 points)
Results: Total Criteria Point Count:
Prognostic Score Interpretation
0 Points:Low (Median Survival of 5.7 yrs)
0.5 - 1 Points:Intermediate 1 (Median Survival of 3.5 yrs.)
1.5 - 2.0 Points:Intermediate 2 (Median Survival of 1.2 yrs.)
2.5-3.5 Points:High (Median Survival of 0.4 yrs.)
  1. Greenberg P, Cox C, LeBeau MM et. al. International Scoring System for Evaluating Prognosis in Myelodysplastic Syndromes. Blood. 1997; 89;6: 2079 - 2088. Erratum in Blood 1998; 91:1100.
  2. Heaney ML, Golde, DW. Medical Progress: Myelodysplasia. NEJM. 1999; 340;21: 1649-1660.
Legal Notices and Disclaimer
All information contained in and produced by the MedCalc 3000 system is provided for educational purposes only. This information should not be used for the diagnosis or treatment of any health problem or disease. THIS INFORMATION IS NOT INTENDED TO REPLACE CLINICAL JUDGMENT OR GUIDE INDIVIDUAL PATIENT CARE IN ANY MANNER. Click here for full notice and disclaimer.
MedCalc 3000 is Copyright © 1998-2011 Foundation Internet Services, LLC    [Build 244179 v11.2.2]
All material on this website is protected by copyright, Copyright © 1994-2016 by WebMD LLC. This website also contains material copyrighted by 3rd parties.