PELD Score for End-Stage Liver Disease (patients less than 12 years old)

Input:
Sex Female

Male
Age
Weight
Height
Albumin
Bilirubin
INR  
Listing Age at listing 1 year or older

Age at listing less than 1 year
Exception Diagnoses Non contributory

Urea cycle disorder

Organic acidemia

Hepatoblastoma
Results:
Growth Failure
PELD Score  
 
PELDScore = 10 * ((0.480 * ln(Bilirubin)) + (1.857 * ln(INR)) - (0.687 * ln(Albumin)) + ListingAgeFactor + Growth)
  • The Pediatric End-stage Liver Disease, or PELD Score, is used to estimate relative disease severity and likely survival of patients awaiting liver transplantation.
  • The Growth term in the equation is set to 0.667 when the subject's height or weight is less than 2 S.D. below the mean values for that age. Thus, the presence of Growth Failure contributes almost 7 points to the PELD score.
  • The Listing Age Factor term will be set to 0.436 if the subject is under 1 year of age, or if the subject is less than 2 years old AND was listed before the age of 1 year.
  • Exception Diagnoses: UNOS specifies urea cycle disorders, organic acidemia and hepatoblastoma as exceptions to the PELD score calculation (and MELD score in patients between 12 and 17 years old). For patients with these diseases, the PELD score is set at 30. Other metabolic diseases may be considered for exception scores by direct petition to UNOS.
  • The United Network for Organ Sharing (UNOS) keeps track of such patients, and has much more information about the PELD score at http://optn.transplant.hrsa.gov/resources/professionalResources.asp?index=8
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