Dosing & Uses
Dosage Forms & Strengths
1 capsule PO q4-6hr PRN
Safety and efficacy not established
Frequency Not Defined
Pruritic maculopapular rash
Hepatitis or severe hepatic/renal impairment
Repeated administration in patients with anemia, cardia, pulmonary, or renal disease
Risk of hepatotoxicity; higher in alcoholics, or with use of more than 1 acetaminophen-containing product
Acetaminophen: Risk for rare, but serious skin reactions that can be fatal; these reactions include Stevens-Johnson Syndrome (SJS), toxic epidermal necrolysis (TEN), and acute generalized exanthematous pustulosis (AGEP); symptoms may include skin redness, blisters and rash
Pregnancy & Lactation
Pregnancy category: C
Lactation: excreted in breast milk
Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Mechanism of Action
Acetaminophen: Acts on hypothalamus to produce antipyresis
Pamabrom: Weak diuretic action
Pyridoxine: Vitamin B6 supplement