No typical dosing guidelines
Traditionally 380-490 mg of powdered yucca stalk or root BID-TID
FDA-approved food additive
Osteoarthritis, hypertension, migraine headaches, colitis, hypercholesterolemia, stomach disorders, diabetes, poor circulation, and liver & gallbladder disorders
Sores, skin diseases, inflammation, bleeding, sprains, broken limbs, joint pain, baldness, & dandruff
Unreliable clinical evidence for the treatment of osteoarthritis
May reduce hypercholesterolemia & hypertension with diet & exercise
None at routine doses
May cause loose stools in high doses
Causes hemolysis in vitro, but never demonstrated in humans
Pregnancy & Lactation
Pregnancy Category: N/A
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Mechanism of Action
May work by blocking intestinal release of toxins that inhibit normal cartilage formation
Contains saponins & the antioxidant resveratrol