oxymetazoline intranasal (OTC)

Brand and Other Names:Afrin, Duramist Plus, more...Dristan 12 Hr, Cheracol Nasal, Duration, Genasal, QlearQuil 12 Hour Nasal Decongestant Moisturizing Spray, Sinarest 12 Hour, Vicks Sinex 12 Hour
  • Print

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

intranasal solution

  • 0.05%
more...

Nasal Congestion

Indicated for temporary relief of nasal congestion

2-3 gtt/sprays per nostril q12hr

Not to exceed 2 doses/24 hr for 3-5 days

Dosage Forms & Strengths

intranasal solution

  • 0.05%
more...

Nasal Congestion

Indicated for temporary relief of nasal congestion

<6 years

  • Safety and efficacy not established

≥6 years

  • 2-3 gtt/sprays per nostril q12hr
  • Not to exceed 2 doses/24 hr for 3-5 days
Next:

Interactions

Interaction Checker

and oxymetazoline intranasal

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

            All Interactions Sort By:
             activity indicator 
            Previous
            Next:

            Adverse Effects

            Frequency Not Defined

            Insomnia

            Headache

            Burning

            Stinging

            Dryness

            Sneezing

            Rebound congestion

            Previous
            Next:

            Warnings

            Contraindications

            Hypersensitivity

            Cautions

            Hypertension

            Heart failure

            Coronary artery disease

            Diabetes

            Hyperthyroidism

            Prostatic hyperplasia

            Overuse may cause rebound congestion

            Previous
            Next:

            Pregnancy & Lactation

            Pregnancy category: C

            Lactation: Not known if excreted in breast milk

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

            more...
            Previous
            Next:

            Pharmacology

            Mechanism of Action

            Alpha-adrenergic agonist; stimulates alpha-adrenergic receptors and produces vasoconstriction in the arterioles of the nasal mucosa

            Absorption

            Onset: Within seconds

            Duration: 6 hr

            Elimination

            Excretion: Via kidney

            Previous
            Next:

            Images

            Previous
            Next: