Valerian (Herbs/Suppl)

Brand and Other Names:all heal, amantilla, more...baldrian, baldrianwurzel, garden heliotrope, herba benedicta, Valeriana edulis, Valeriana jatamansii, Valeriana officinalis, Valeriana sitchensis, valeriana spp, Valeriana wallichii
  • Print

Suggested Dosing

Insomnia

Aqueous Extract: 400-900 mg PO up to 2 hours before bedtime

Ethanolic extract: 600 mg PO HS

Root (fresh or dried): 2-3 g PO qDay-TID

Combinations with hops or lemon balm: 320-500 mg PO HS

No more than 28 days

Next:

Suggested Uses

Insomnia/sleep disorders, ADHD, anxiety disorders, depression, epilepsy, infantile convulsions, menopausal symptoms, menstrual cramps, restlessness, tremors

Efficacy

Promotes falling asleep, but does not reduce night awakenings

Does not relieve insomnia as fast as benzodiazepines

Previous
Next:

Interactions

Interaction Checker

and Valerian

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

            All Interactions Sort By:
             activity indicator 
            Previous
            Next:

            Adverse Effects

            Frequency Not Defined

            Cardiac disturbances

            Excitability

            Headache

            Hepatotoxicity

            Insomnia

            Morning drowsiness

            Sedation

            Uneasiness

            Withdrawal syndrome (chronic use)

            Previous
            Next:

            Warnings

            Contraindications

            None reported

            Cautions

            Concurrent CNS depressants

            Concurrent CYP 3A4 substrates

            Previous
            Next:

            Pregnancy & Lactation

            Pregnancy Category: avoid use

            Lactation: avoid use

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

            more...
            Previous
            Next:

            Pharmacology

            Metabolism: N/A

            Excretion: N/A

            Mechanism of Action

            Active constituents: valepotriates

            Inhibits re-uptake of GABA

            Previous