Close
New

Medscape is available in 5 Language Editions – Choose your Edition here.

 

loteprednol ophthalmic (Rx)Brand and Other Names:Alrex, Lotemax

 
 
 

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

ophthalmic suspension

  • 0.2% (Alrex)
  • 0.5% (Lotemax)

ophthalmic ointment

  • 0.5% (Lotemax)

ophthalmic gel

  • 0.5% (Lotemax)
more...

Seasonal Allergic Conjunctivitis

0.2% suspension: 1 gtt into affected eye QID

Steroid-Responsive Inflammatory Conditions

Indicated for the treatment of steroid-responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe (eg, allergic conjunctivitis, acne rosacea, superficial punctate keratitis, herpes zoster keratitis, iritis, cyclitis, selected infective conjunctivitides)

0.5% suspension: 1-2 gtt into conjunctival sac of the affected eye(s) QID; if necessary, may increase dose up to 1 gtt every hour during initial treatment within the first week

Re-evaluate if signs and symptoms do not improve after 2 days

Postoperative Ocular Inflammation

0.5% suspension or gel: Apply 1-2 gtt into the conjunctival sac of the operated eye(s) QID beginning 24 hr after surgery and continuing throughout the first 2 weeks of the postoperative period

0.5% ointment: Apply small amount (~0.5-in ribbon) into conjunctival sac(s) QID beginning 24 hr after surgery and continue throughout the first 2 weeks of the postoperative period

Safety and efficacy not established

Next

Adverse Effects

Frequency Not Defined

Glaucoma

Cataract

Potentiate super infection

Slow wound healing

Blurred vision

Burning sensation in eye

Itching of eye

Light intolerance

Raised intraocular pressure

Previous
Next

Warnings

Contraindications

Hypersensitivity to any component of the formulation

Absolute: herpes simplex (keratitis, dendritic), keratitis (vaccinia virus), ocular infection (fungal), ocular infection (viral), ocular tuberculosis

Relative: glaucoma

Cautions

Close monitoring should occur: ocular surgery

Previous
Next

Pregnancy & Lactation

Pregnancy Category: C

Lactation: ophthalmic corticosteroids have not been reported to cause problems in nursing babies

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

more...
Previous
Next

Pharmacology

Mechanism of Action

Synthetic nonfluorinated corticosteroid

Pharmacokinetics

Absorption: Following topical instillation into the conjunctival sac, absorbed into the aqueous humor and minimal systemic absorption occurs

Previous
Next

Images

Previous
Next

Formulary

FormularyPatient Discounts

To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.

Adding plans allows you to:

  • View the formulary and any restrictions for each plan.
  • Manage and view all your plans together – even plans in different states.
  • Compare formulary status to other drugs in the same class.
  • Access your plan list on any device – mobile or desktop.

The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

Tier Description
1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
NC NOT COVERED – Drugs that are not covered by the plan.
Code Definition
PA Prior Authorization
Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
QL Quantity Limits
Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
ST Step Therapy
Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
OR Other Restrictions
Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
Add or Remove Plans
Plans for
Select State:
Non-Medicare PlansMedicare Plans

Select a box to add or remove a plan.

Select a class to view formulary status for similar drugs

Additional Offers
Email to Patient

From:

To:

The recipient will receive more details and instructions to access this offer.

By clicking send, you acknowledge that you have permission to email the recipient with this information.

Email Forms to Patient

From:

To:

The recipient will receive more details and instructions to access this offer.

By clicking send, you acknowledge that you have permission to email the recipient with this information.

Previous
 
 
 
All material on this website is protected by copyright, Copyright © 1994-2016 by WebMD LLC. This website also contains material copyrighted by 3rd parties.