Brand and Other Names:American cranberry, black cranberry, more...European cranberry, low cranberry, mossberry, Oxycoccus macrocarpus, trailing swamp cranberry, Vaccinium edule, Vaccinium erythrocarpum, vaccinium macrocarpon, Vaccinium occycoccus, Vaccinium vitis
- Classes: Urology, Herbals
- Cranberry juice cocktail (26% cranberry juice): 10-16 oz/day PO
- Cranberry juice: 15 mL BID PO
- 400 mg BID PO
Urinary Deodorizer for Incontinent Patients
Cranberry juice cocktail
- 3-6 oz/day PO
UTI (prevention), urinary deodorizer for incontinent patients, type 2 diabetes, chronic fatigue syndrome, scurvy, pleurisy, as a diuretic, antiseptic, antipyretic, & cancer
Studies show significant reduction in the risk of recurrent UTI's in the elderly, hospitalized patients, and pregnant women
No reliable evidence shows effectiveness for treating UTI
Urinary odor: Preliminary research shows there may be a reduction in urinary odor in patients receiving oral cranberry
Diabetes: Clinical studies show NO improvement in fasting blood glucose, HbA1c, fructosamine, triglyceride, HDL cholesterol, or LDL cholesterol levels in patients with type 2 diabetes
Serious - Use Alternative
Significant - Monitor Closely
GI upset, diarrhea, kidney stones at high doses
Increased risk of cancer oxalate uroliths in predisposed patients
History of kidney stones
Atrophic gastritis, hypochlorhydria
Potential interaction with warfarin & increased bleeding risk
No evidence for efficacy in treatment
Pregnancy & Lactation
Pregnancy Category: avoid use
Lactation: avoid use
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Mechanism of Action
Proanthocyanidins, other compounds prevent bacterial adherence to urothelium
Does not significantly decrease urine pH