Dosing & Uses
Dosage Forms & Strengths
Hemorrhoids, Anal fissures, Pruritus ani
Apply BID to areas of discomfort and anal opening
Safety and efficacy not established
Frequency Not Defined
Cutaneous and subcutaneous atrophy
Dry scaly skin
Echymoses and petechia
Impaired wound healing
Systemic absorption of topical corticosteroids may cause hypothalamic-pituitary axis suppression when applied over large surface areas; other adverse effects include hyperglycemia, HPA suppression, glycosuria, fluid and electrolyte changes, hyperglycemia etc
Allergic contact dermatitis
Prolonged treatment with corticosteroids is associated with development of Kaposi’s sarcoma
Discontinue if infection develops.
Pregnancy & Lactation
Pregnancy Category: C
Lactation: Unknown if distributed in breast milk; exercise caution
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Mechanism of Action
Combination therapy; anti-inflammatory, antipruritic, and vasoconstrictive effects
Rectal absorption: 26%
Insert applicator gently into anal area when administering
For external use only; avoid contact with eyes, nose, or ears
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|1||This drug is available at the lowest co-pay. Most commonly, these are generic drugs.|
|2||This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.|
|3||This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.|
|4||This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.|
|5||This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.|
|6||This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.|
|NC||NOT COVERED – Drugs that are not covered by the plan.|
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