Improving muscle strength & size
50-150 mg PO BID
Improve strength, athletic performance
Demonstrated to increase endogenous testosterone production, but no conclusive effects on muscle mass
Serious - Use Alternative
Significant - Monitor Closely
Expected to be similar to exogenous testosterone:
Men: acne, decreased endogenous testosterone, testicular atrophy, gynecomastia, increased risk of prostate cancer
Women: clitoral hypertrophy, hirsutism, acne, amenorrhea
Adolescents: early closing of growth plates, decreased adult height
Pregnancy & Lactation
Pregnancy Category: N/A
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Mechanism of Action
Precursor of estrone and testosterone