Fennel (Herbs/Suppl)

Brand and Other Names:aneth doux, bitterfenchel, more...fenchel, foeniculum vulgare
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Suggested Dosing

Tea

1-2 g crushed seed in 150 mL boiling water

Tincture

5-7.5 g/day PO

Fennel oil

01.-0.6 mL; no more than 2 weeks

Capsules

Take 1-2 caps (480-960 mg) qDay-TID, preferably with food

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Suggested Uses

Treatment of infants & nursing children suffering from colic & dyspeptic disease

Digestive aid

URI, cough & sore throat

Reduces pain associated with menstrual cramps (dysmenorrhea)

Increase milk secretion, promote menstruation, facilitate birth, alleviate male climacteric (andropause) symptoms, & incr libido

Antiinflammatory, analgesic & antioxidant properties

Efficacy

Colic: A clinical trial showed breast-fed infants with colic had decreased crying time

Insufficient reliable information about effectiveness for other uses

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Interactions

Interaction Checker

and Fennel

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    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Breathing problems, tightness of chest/throat, chest pain, nausea & vomiting, skin hives, rash, itchy or swollen skin, mild increase in menstrual flow, sun sensitivity, seizures

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            Warnings

            Contraindications

            Hypersensitivity to carrots, celery or mugwort

            Concomitant antibiotics

            Cautions

            Pregnant or breastfeeding: seek physician advice

            Pregnancy: do not use fennel preparations other than fennel honey & fennel seed infusions

            Children: use only fennel honey

            Epilepsy or seizure d/o

            Do not use Fennel for a long time or in large quantities

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            Pregnancy & Lactation

            Pregnancy Category: use only fennel honey & fennel seed infusions

            Lactation: may increase milk flow, consult physician

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Pharmacology

            Metabolism: N/A

            Excretion: N/A

            Mechanism of Action

            PO admin (200 mg/kg) of fruit methonolic extract:

            • significantly increase plasma superoxide dismutase & catalase activity and HDL cholesterol levels
            • inhibitory effect against acute & subacute inflammatory diseases & type IV allergic rxn
            • showed central analgesic effect

            Fennel seed oil: reduces intestinal spasms & increases motility of small intestine

            Hepatoprotection: inhibits hepatotoxicity by decreasing levels of AST, ALT, ALP & bilirubin

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