15-30 mg PO daily
Bark tincture: 5-10 gtt PO TID
Yohimbe bark: Potential for side effects
Numerous regimens available, follow mfct recommendations
Erectile dysfunction, sexual dysfunction (male or female), sexual dysfunction (SSRI-induced)
Possibly effective for impotence
Serious - Use Alternative
Significant - Monitor Closely
Anxiety, cardiac coduction disturbances, cardiac failure, dizziness, excitation, fluid retention, gastric intolerance, headache, hypertension, hypotension, insomnia, irritability, nausea/vomiting, paralysis, respiratory depression, salivation, sinusitis, tachycardia, tremor, urinary frequency
Angina, anxiety, BPH, concomitant MAO inhibitors, concomitant sympathomimetic drugs, depression, diabetes mellitus, heart disease, hypertension, hypotension, kidney disease, liver disease, post-traumatic stress disorder, prostate inflammation, tyramine-containing foods
Pregnancy & Lactation
Pregnancy Category: unsafe
Lactation: avoid use
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Mechanism of Action
Yohimbine is an alpha-2-adrenergic blocker