tuberculin purified protein derivative (Rx)Brand and Other Names:Aplisol, Mantoux, more...PPD, Sclavo PPD Soln, Tubersol

 
 
 

Dosing & Uses

AdultPediatricGeriatric

Dosage Forms & Strengths

Intradermal solution

  • 5 Unit/0.1mL
more...

Tuberculosis

Diagnosis: Mantoux test, inject 0.1 mL (5 tuberculin units) intradermally; the result is read 48 to 72 hours after administration

Positive if 10 mm induration

Use 1 TU in sensitized patients, 250 TU if no response to 5 TU

Dosage Forms & Strengths

Intradermal solution

  • 5 Unit/0.1mL
more...

Tuberculosis

Diagnosis: Mantoux test, inject 0.1 mL (5 tuberculin units) intradermally; the result is read 48 to 72 hours after administration  

Positive if 10 mm induration

Use 1 TU in sensitized patients, 250 TU if no response to 5 TU

Tuberculosis

Diagnosis: Mantoux test, inject 0.1 mL (5 tuberculin units) intradermally; the result is read 48-72 hours after administration  

Positive if >10 mm induration

Use 1 TU in sensitized patients, 250 TU if no response to 5 TU

Next

Adverse Effects

Suspected adverse events after administration of any vaccine may be reported to Vaccine Adverse Events Reporting System (VAERS), 1-800-822-7967

Frequency Not Defined

Rash

Itch

Vesiculation

Ulceration

Necrosis

Pain

Previous
Next

Warnings

Contraindications

Previous positive tuberculin skin test responsiveness suppressed within 6 weeks of viral infection, inactive TB, immunosuppression, geriatric

Cautions

Contains soluble growth products from tubercle bacillus

Old tuberculin (OT) is culture filtrate of uniform potency

PPD is more refined and is preferred product

Multiple puncture device (Aplitest, SclavoTest-PPD, Tine Test PPD) not as sensitive

Previous
Next

Pregnancy & Lactation

Pregnancy Category: C

Lactation: not known if excreted in breast milk

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

more...
Previous
Next

Pharmacology

Mechanism of Action

Antigenic purified protein derivative (PPD) of Mycobacterium tuberculosis; patients become sensitized to certain antigenic components of the M. tuberculosis organism.

Pharmacokinetics

Onset of action: 5-6hr (delayed hypersensitivity reactions)

Peak effect: 48-72 hr

Previous
Next

Images

Previous
Next

Formulary

FormularyPatient Discounts

To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.

Adding plans allows you to:

  • View the formulary and any restrictions for each plan.
  • Manage and view all your plans together – even plans in different states.
  • Compare formulary status to other drugs in the same class.
  • Access your plan list on any device – mobile or desktop.

The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

Tier Description
1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
NC NOT COVERED – Drugs that are not covered by the plan.
Code Definition
PA Prior Authorization
Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
QL Quantity Limits
Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
ST Step Therapy
Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
OR Other Restrictions
Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
Add or Remove Plans
Plans for
Select State:
Non-Medicare PlansMedicare Plans

Select a box to add or remove a plan.

Select a class to view formulary status for similar drugs

Additional Offers
Email to Patient

From:

To:

The recipient will receive more details and instructions to access this offer.

By clicking send, you acknowledge that you have permission to email the recipient with this information.

Email Forms to Patient

From:

To:

The recipient will receive more details and instructions to access this offer.

By clicking send, you acknowledge that you have permission to email the recipient with this information.

Previous
 
 
 
All material on this website is protected by copyright, Copyright © 1994-2016 by WebMD LLC. This website also contains material copyrighted by 3rd parties.