120-240 mg salicin PO TID-QID
1-3 g PO TID-QID
1 cup PO TID-QID; prepared with 1-3 g bark/150 ml water
1-3 ml PO qDay; 1:1 25% alcohol
Fever, gouty arthritis, headaches, inflammation, influenza symptoms, muscle/joint aches, pain, rheumatoid arthritis
Serious - Use Alternative
Significant - Monitor Closely
Frequency Not Defined
Blood in stool
Skin rash (topical use)
Aspirin hypersensitivity, asthma, diabetes mellitus, gout, hemophilia, hypoprothrombinemia, kidney disease, liver disease, PUD, viral infection (peds)
Pregnancy & Lactation
Pregnancy Category: N/A
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Mechanism of Action
Contains salicin, which is converted to salicylic acid