Phytosterols (Herbs/Suppl)

Brand and Other Names:Bayer Heart Health Advantage, benecol margarine, more...cholestatin, stigmasterol
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Suggested Dosing

Hypercholesterolemia

1200 mg/day PO capsules

1-2 Tbs 1-3 times daily as functional foods (margarine, salad dressing)

Bayer Heart Health Advantage

  • 12 years or older: 400 mg PO BID with meals

Benign Prostatic Hyperplasia

60 -130 mg/day PO divided BID/TID of beta-sitosterol

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Suggested Uses

Hypercholesterolemia, Benign prostatic hyperplasia (BPH).

Efficacy

Proven effective in lowering LDL in conjunction with diet & exercise

Improves urinary symptoms with BPH

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Adverse Effects

Frequency Not Defined

Xanthomatosis

Atherosclerosis in patients with sitosterolemia (very rare)

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Warnings

Contraindications

N/A

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Pregnancy & Lactation

Pregnancy Category: N/A

Lactation: N/A

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

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Pharmacology

Metabolism: N/A

Excretion: N/A

Mechanism of Action

Plant-derived sterols; decr cholesterol absorption from small intestine

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