Dosing & Uses
Dosage Forms & Strengths
Analgesia for Minor Muscle/Joint Pain
Apply liberal amounts of cream/gel topically to affected area and massage
Apply patch to affected area q12hr
Safety and efficacy not established
Frequency Not Defined
Stinging/burning/tingling sensation of skin
Topical use only
Pregnancy & Lactation
Pregnancy Category: C
Lactation: Unknown whether distributed in breast milk; use caution
Pregnant or breastfeeding patients should seek advice of healthcare professional before using OTC drugs
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Mechanism of Action
Produces counterirritation; stimulates TRPM8 receptors