Brand and Other Names:Bepreve
- Classes: Antihistamines, Ophthalmic
Dosing & Uses
Dosage Forms & Strengths
- 1.5% (10mL)
Instill 1 gtt into affected eye(s) BID
Dosage Forms & Strengths
- 1.5% (10mL)
<2 years old: Safety & efficacy not established
>2 years old: Administer as in adults; instill 1 gtt into affected eye(s) BID
Mild taste disturbance
Hypersensitivity reactions, including itching, body rash, and swelling lips, tongue and/or throat
Remove contact lenses prior to instillation
Store at room temp; protect from light & excessive heat
To prevent contamination do not touch dropper tip to any surface
Keep bottle tightly closed when not in use
Pregnancy & Lactation
Pregnancy Category: C
Lactation: excretion in milk unknown; use with caution
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Cmax: 5.1-7.3 ng/mL
Absorption: Minimal systemic absorption
Protein Bound: 55%
Metabolism: Minimally metabolized by CYP450 isozymes
Excretion: urine (75-90% excreted unchanged)
Mechanism of Action
Topical H1 receptor antagonist; inhibits histamine release from mast cells
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|1||This drug is available at the lowest co-pay. Most commonly, these are generic drugs.|
|2||This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.|
|3||This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.|
|4||This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.|
|5||This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.|
|6||This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.|
|NC||NOT COVERED – Drugs that are not covered by the plan.|
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