60mg PO BID-TID
600 mg PO TID
1 cup PO TID; 600 mg dried leaves/150 ml water
Topical: apply 1% cream daily
Abdominal disorders, aphrodisiac, common cold/flu, fatigue, memory enhancer, varicose veins, venous insufficiency
Topical: hypertrophic scarring, psoriasis, wound healing
Possibly effective for listed uses
Serious - Use Alternative
Significant - Monitor Closely
Frequency Not Defined
Topical: Allergic contact dermatitis
Large dose: Drowsiness
Concurrent sedative agents, diabetes mellitus, hyperlipidemia
Pregnancy & Lactation
Pregnancy Category: avoid use
Lactation: avoid use
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Mechanism of Action
Triterpene compounds stimulate connective tissue repair, keratinization
Asiaticoside derivatives protect neurons from beta-amyloid toxicity