butalbital (Discontinued)

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Brand and Other Names:

Dosing & Uses

AdultPediatric

Combos

With acetaminophen: Fioricet

With ASA: Fiorinal

Other Indications & Uses

Pain, vascular HA

<12 years: Safety and efficacy not established

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Interactions

Interaction Checker

and butalbital

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    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Frequency Not Defined

            Common

            • Dizziness
            • Drowsiness
            • Intoxicated feeling
            • Lightheadedness
            • Sedation

            Less Common

            • Tachycardia
            • Headache, shaky feeling, tingling, agitation, fainting, fatigue, fever, heavy eyelids, high energy, hot spells, numbness, sluggishness, seizure
            • Dry mouth, hyperhidrosis
            • Difficulty swallowing, heartburn, flatulence, constipation
            • Leg pain, muscle fatigue
            • Diuresis
            • Pruritus, earache, nasal congestion, tinnitus, euphoria, allergic reactions
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            Warnings

            Contraindications

            Hypersensitivity to any component, porphyria

            Cautions

            Patient should avoid driving car, heavy machinery

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            Pregnancy & Lactation

            Pregnancy Category: C

            Lactation: excreted in breast milk

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Pharmacology

            Half-Life: 35 hr

            Excretion: renal (Butalbital)

            Mechanism of Action

            Butalbital: intermediate-acting barbiturate

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