1-10 cups PO qD; 1 tsp tea leaves/ 8 oz boiling water
1 cup or 60 mg caffeine (3 cups = 240-320 mg polyphenols)
Cancer (prevention), cognitive improvement, Crohn's disease, diuresis, genital warts, headaches, heart disease (prevention), Parkinson's disease (prevention), stomach disorders, weight loss (combination products), hypercholesterolemia
Possibly effective for listed uses
Studies show benefit in prevention of bladder, esophageal, pancreatic cancer; neg. results for stomach cancer
Serious - Use Alternative
Significant - Monitor Closely
Frequency Not Defined
Loss of appetite
Avoid prior to surgery: may cause bleeding
Anxiety disorders, arrhythmias, cardiac disease, depression, diabetes mellitus, hypertension, kidney disease, ulcers (gastric/duodenal)
Pregnancy & Lactation
Pregnancy Category: avoid use
Lactation: avoid use
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Mechanism of Action
Contains polyphenols (flavonoids): antioxidant, reduce DNA oxidative damage, inhib. carcinogen formation (e.g., nitrosamines)
Caffeine: CNS stimulant