Chamomile (Herbs/Suppl)

Brand and Other Names:chamomilla recutita, German chamomile, more...matricaria chamomilla, matricaria recutita, pin heads, Roman chamomile, wild chamomile
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Suggested Dosing

Mucositis, chemo-induced

Swish orally and swallow TID; use 10-15 drops liquid extract / 100 ml warm water

Dyspepsia

1 mL PO TID (Iberogast, Medical Futures, Inc)

Dried flower heads

2-8 g PO TID

Tea

1 cup PO TID-QID; 3 g dried flower heads/150 ml water

Liquid extract

1-4 ml PO TID; 1:1 in 45% alcohol

Tea poultice/rinse

Apply 3-10% ointment/gel PRN

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Suggested Uses

Flatulence, GI inflammatory disorders, GI spasms, inflammation (skin or mucous membrane), insomnia, menstrual cramps, motion sickness

Topical: hemorrhoids, mucositis (chemo-induced)

Efficacy

Classified as effective by German Commission E

Possibly effective for dyspepsia, colic and mucositis

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Adverse Effects

Frequency Not Defined

Generally regarded as safe

Anaphylaxis

Contact dermatitis

Hypersensitivity reactions

Vomiting

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Warnings

Contraindications

Hypersensitivity to Asteraceae/Compositae plants chrysanthemums, daisies, marigolds, ragweed

Cautions

Asthma, concurrent CYP 3A4 substrates

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Pregnancy & Lactation

Pregnancy Category: avoid use

Lactation: N/A

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

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Pharmacology

Metabolism: N/A

Excretion: N/A

Mechanism of Action

Tiglic acid esters: antispasmodic, anti-inflammatory

Chamazulene: antispasmodic, anti-inflammatory, anti-allergic, antibacterial

Apigenin: anti-inflammatory (comparable to NSAIDs)

Azulene: anti-inflammatory

Umbelliferone: fungicidal

Bisabolols: antimicrobial, antipyretic, anti-inflammatory, antispasmodic

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