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dexamethasone/ciprofloxacin (Rx)Brand and Other Names:Ciprodex

 
 
 

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

ciprofloxacin/dexamethasone

otic suspension

  • 0.3%/0.1%
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Acute Otitis Externa

4 drops in affected ear q12hr for 7 days

Dosage Forms & Strengths

ciprofloxacin/dexamethasone

otic suspension

  • 0.3%/0.1%
more...

Acute Otitis Media with Tympanostomy Tubes, Acute Otitis Externa

<6 months: Not recommended

>6 months: 4 drops in affected ear q12hr for 7 days

For acute otitis media, administer through tympanostomy tube

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Adverse Effects

Frequency Not Defined

Alopecia

Dermatitis

Dysgeusia

Fungal dermatitis

Headache

Hyperesthesia

Migraine headache

Paresthesias

Pruritus

Rash

Urticaria

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Warnings

Contraindications

Hypersensitivity to any component (contains benzalkonium chloride)

Fungal or viral infections of external canal, including varicella and herpes simplex virus infections

Cautions

Discontinue if hypersensitivity or superinfection occurs

Reevaluate if no improvement is noted after 1 week

Prolonged use may result in overgrowth of non-susceptible bacteria and fungi

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Pregnancy & Lactation

Pregnancy category: C

Lactation: Unknown whether drug is excreted in milk; use not recommended

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

more...
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Pharmacology

Mechanism of Action

Ciprofloxacin: Inhibits DNA gyrase and topoisomerase IV; bactericidal

Dexamethasone: Suppresses inflammatory response associated with bacterial infections

Absorption

Negligible systemic absorption

Peak plasma time: 15 min to 2 hr

Elimination

Excretion: Urine

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Images

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Formulary

FormularyPatient Discounts

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The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

Tier Description
1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
NC NOT COVERED – Drugs that are not covered by the plan.
Code Definition
PA Prior Authorization
Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
QL Quantity Limits
Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
ST Step Therapy
Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
OR Other Restrictions
Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
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