dexamethasone/ciprofloxacin (Rx) - Ciprodex

 
 
 

Adult Dosing & Uses

Dosing Forms & Strengths

ciprofloxacin/dexamethasone

otic suspension

  • 0.3%/0.1%

Acute Otitis Externa

4 gtt in affected ear BID x7 days

Other Indications & Uses

Acute otitis media in children

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Pediatric Dosing & Uses

Dosing Forms & Strengths

ciprofloxacin/dexamethasone

otic suspension

  • 0.3%/0.1%

Acute Otitis Media with Tympanostomy Tubes, Acute Otitis Externa

<6 months old: Not recommended

6 months or older: 4 gtt in affected ear BID x7 days

Administration

AOM: Administer through tympanostomy tube

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Adverse Effects

Frequency Not Defined

Headache

Migraine headache

Dysguesia

Hyperesthesia

Paresthesias

Pruritis

Fungal dermatitis

Rash

Dermatitis

Urticaria

Alopecia

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Contraindications & Cautions

Contraindications

Hypersensitivity to any component (contains benzalkonium chloride)

Fungal or viral infections of external canal including varicella & herpes simplex infections

Cautions

Discontinue if hypersensitivity or superinfection occurs

Re-evaluate if no improvement after 1 wk

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View Category Definitions

Pregnancy & Lactation

Pregnancy Category: C

Lactation: excretion in milk unknown/not recommended

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

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Pharmacology

Mechanism of Action

Ciprofloxacin: Inhibits DNA gyrase & topoisomerase IV; bactericidal

Dexamethasone: suppresses inflammatory response

Pharmacokinetics

Absorption: negligible systemic

Excretion: urine

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Pricing & Images

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