No typical dosage
>4 glasses juice/day for pharmacologic effects OR
1 to 9 glasses daily, or 240 mL of double-strength juice BID
Atherosclerosis, asthma, atopic dermatitis, cancer, fiber supplement, hematocrit reduction, hypercholesterolemia, potassium supplement, psoriasis, vitamin C supplement, weight loss aid
Insufficient reliable evidence
Serious - Use Alternative
Significant - Monitor Closely
Concurrent CYP3A4 substrates
Concurrent interactive agents
Pregnancy & Lactation
Pregnancy Category: avoid excess
Lactation: avoid excess
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Enzyme Inhibited: CYP3A4
Mechanism of Action
Source of potassium, vit C, pectin
Pectin decrease cholesterol & promote regression of atherosclerosis