Grapefruit (Herbs/Suppl)

Brand and Other Names:citrus paradisi, pomelo, more...toronja
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Suggested Dosing

No typical dosage

>4 glasses juice/day for pharmacologic effects OR

1 to 9 glasses daily, or 240 mL of double-strength juice BID

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Suggested Uses

Atherosclerosis, asthma, atopic dermatitis, cancer, fiber supplement, hematocrit reduction, hypercholesterolemia, potassium supplement, psoriasis, vitamin C supplement, weight loss aid

Efficacy

Insufficient reliable evidence

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Interactions

Interaction Checker

and Grapefruit

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Decreased hematocrit

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            Warnings

            Contraindications

            None reported

            Cautions

            Concurrent CYP3A4 substrates

            Concurrent interactive agents

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            Pregnancy & Lactation

            Pregnancy Category: avoid excess

            Lactation: avoid excess

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Pharmacology

            Metabolism: N/A

            Excretion: N/A

            Enzyme Inhibited: CYP3A4

            Mechanism of Action

            Source of potassium, vit C, pectin

            Pectin decrease cholesterol & promote regression of atherosclerosis

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