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glycerin rectal (OTC)Brand and Other Names:Colace Infant/Child Suppositories, Colace Suppositories, more...Fleet Glycerin Suppositories, Fleet Liquid Glycerin Suppositories, Pedia-Lax Glycerin Suppositories, Pedia-Lax Liquid Glycerin Suppositories

 
 
 

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

liquid suppository

  • 5.6g/5.5mL

suppository

  • 2g
  • 2.1g
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Occasional Constipation

suppository

  • 2-2.1 g suppository inserted in rectum, retain for about 15 min

liquid suppository

  • 5.6 g liquid suppository inserted in rectum; retain for about 15 min

Maximum: 1 suppository or liquid suppository/day

Administration

Patient should lie on left side with knees bent

Remove protective wrap before inserting

Gently insert tip into rectum with slight side-to-side movement (tip of suppository pointing toward navel)

For liquid suppository, squeeze bulb until all liquid is expelled and discard unit

Dosage Forms & Strengths

liquid suppository

  • 2.3g/2.3mL
  • 5.6g/5.5mL

suppository

  • 1g
  • 1.2g
  • 2g
  • 2.1g
more...

Occasional Constipation

suppository

  • 2-5 years: 1-1.2 g suppository inserted in rectum, retain for about 15 min
  • >5 years: 2-2.1 g suppository inserted in rectum, retain for about 15 min

liquid suppository

  • 2-5 years: 2.3 g pediatric liquid suppository inserted in rectum; retain for about 15 min
  • >5 years: 5.6 g liquid suppository inserted in rectum; retain for about 15 min

Maximum: 1 suppository or liquid suppository/day

Administration

Patient should lie on left side with knees bent

Remove protective wrap before inserting

Gently insert tip into rectum with slight side-to-side movement (tip of suppository pointing toward navel)

For liquid suppository, squeeze bulb until all liquid is expelled and discard unit

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Adverse Effects

Frequency Not Defined

Rectal discomfort

Burning sensation

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Warnings

Contraindications

Hypersensitivity

Cautions

Do not use when abdominal pain, nausea, or vomiting present (unless directed by physician)

Frequent or prolonged use of laxatives may result in dependence

Rectal bleeding or failure to have bowel movement requires physician care

Contact physician before use if sudden change in bowel habits that last >2 wk

Do not use for longer than 1 wk

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Pregnancy & Lactation

Pregnancy category: C

Lactation: unknown, but probably compatible with breastfeeding

Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

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Pharmacology

Onset: 15-60 min

Mechanism of Action

Hyperosmotic laxative; attracts water into stool and elicits bowel movement

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