Guggul (Herbs/Suppl)

Brand and Other Names:commiphora mukul, gugulipid
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Suggested Dosing

500 mg PO TID standardized extract

Gugulipid: standardized to 5% guggulsterone

Nodulocystic Acne

Dose of the guggulipid equivalent up to 25 mg guggulsterones twice a day has been used

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Suggested Uses

Type IIb, type IV hyperlipidemias, nodulocystic acne.

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Interactions

Interaction Checker

and Guggul

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    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Frequency Not Defined

            Rash

            Diarrhea associated with crude gum guggul

            Standardized gugulipid much less toxic

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            Warnings

            Contraindications

            See product label

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            Pregnancy & Lactation

            Pregnancy Category: N/A

            Lactation: N/A

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Pharmacology

            Metabolism: N/A

            Excretion: N/A

            Mechanism of Action

            Increase LDL uptake by liver; stimulates thyroid function

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