phenylephrine PO (Rx, OTC)

Brand and Other Names:Contac D
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

tablet

  • 5mg
  • 10mg
more...

Nasal Congestion

1-2 tablets (10-20 mg) PO q4hr PRN; not to exceed 60 mg/24 hr

Dosage Forms & Strengths

tablet

  • 5mg
  • 10mg
more...

Nasal Congestion

<6 years: Consult a pediatrician

6-12 years: 1 tablets (10 mg) PO q4hr PRN; not to exceed 30 mg/24 hr

>12 years: 1-2 tablets (10-20 mg) PO q4hr PRN; not to exceed 60 mg/24 hr

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Interactions

Interaction Checker

and phenylephrine PO

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Frequency Not Defined

            Palpitation

            Tachycardia

            Premature ventricular contractions

            Occipital headache

            Insomnia

            Resltessness

            Gastric irritation

            Tremor

            Pallor or blanching

            Trembling or tremors

            Increased perspiration

            Respiratory distress

            Hypertension

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            Warnings

            Contraindications

            Hypersensitivity, hypertension, ventricular tachycardia

            Nonselective MAO inhibitors (risk of hypertensive reaction)

            Cautions

            Some products may contain sulfites, which may cause allergic reactions in susceptible individuals

            Closely monitor in hyperthyroidism, DM, heart disease, bowel obstruction/narrowing, increased intraocular pressure, BPH

            Discontinue and inform healthcare provider if dizziness, nervousness, or sleeplessness occur

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            Pregnancy & Lactation

            Pregnancy Category: C

            Lactation: Not known if excreted in breast milk

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Pharmacology

            Mechanism of Action

            Alpha adrenergic agonist that produces systemic arterial vasoconstriction

            Pharmcokinetics

            Absorption: Rapid and complete

            Duration: 2-4 hr (decongestant)

            Onset: 15-30 min

            Vd: 26-61 L

            Metabolism: Liver & intestine by MAO

            Excretion: Urine

            Bioavailability: <38%

            Half-life elimination: 2-3hr (terminal phase)

            Peak plasma time: 0.75-2 hr

            Excretion: Urine

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            Formulary

            FormularyPatient Discounts

            Adding plans allows you to compare formulary status to other drugs in the same class.

            To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.

            Adding plans allows you to:

            • View the formulary and any restrictions for each plan.
            • Manage and view all your plans together – even plans in different states.
            • Compare formulary status to other drugs in the same class.
            • Access your plan list on any device – mobile or desktop.

            The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

            Tier Description
            1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
            2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
            3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
            4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            NC NOT COVERED – Drugs that are not covered by the plan.
            Code Definition
            PA Prior Authorization
            Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
            QL Quantity Limits
            Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
            ST Step Therapy
            Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
            OR Other Restrictions
            Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
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