Dosing & Uses
Dosage Forms & Strengths
- 0.4mg/mL (10mL)
2-5 mg PO qDay or more; not to exceed 8 mg/day
Alternatively (parenteral nutrition): 0.3-0.5 mg/day IV or 0.5-1.5 mg/day IV (per manufacturer)
High Output Fistula
- May use twice the recommended daily allowance
- Males: 900 mcg/day
- Females: 900 mcg/day
- Pregnant: 1,000 mcg/day
- Nursing: 1,300 mcg/day
- UL (>19 years old): 10,000 mcg/day
Dosage Forms & Strengths
- 0.4mg/mL (10mL)
Parenteral nutrition: 20 mcg copper/kg/day IV
- 0-6 months old: 200 mcg/day
- 7-12 months old: 220 mcg/day
- 1-3 years old: 340 mcg/day
- 3-8 years old: 440 mcg/day
- 8-13 years old: 700 mcg/day
- 13-18 years old: (Male, Female) 890 mcg/day
Serious - Use Alternative
Significant - Monitor Closely
Frequency Not Defined
Nausea/vomiting (10-60 mg dose)
Hepatic dysfunction including necrosis
None listed by manufacturer
Administration not recommended in Wilson disease
Use caution in patients with hepatic impairment
Injection contains aluminum; use caution in renal impairment and premature infants
Acidic pH of the solution may cause tissue irritation
Pregnancy & Lactation
Pregnancy Category: C
Lactation: Excretion in milk unknown; use with caution
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Mechanism of Action
Cofactor in many enzymes, including ceruloplasmin; involved in formation of iron carrier protein, transferrin
Helps maintain normal rates of red and white blood cell formation and helps prevent development of deficiency symptoms
Excretion: Intestinal wall, urine, and bile
Not for direct administration; must dilute; administer only after dilution in not less than 100 mL
No preservatives - use promptly & discard unused portion
Adding plans allows you to compare formulary status to other drugs in the same class.
To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.
Adding plans allows you to:
- View the formulary and any restrictions for each plan.
- Manage and view all your plans together – even plans in different states.
- Compare formulary status to other drugs in the same class.
- Access your plan list on any device – mobile or desktop.
The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.
|1||This drug is available at the lowest co-pay. Most commonly, these are generic drugs.|
|2||This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.|
|3||This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.|
|4||This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.|
|5||This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.|
|6||This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.|
|NC||NOT COVERED – Drugs that are not covered by the plan.|
Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.