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Coenzyme Q10 (Herbs/Suppl)Brand and Other Names:CoQ10, ibedenone, more...mitoquinone, ubidecarenone, ubiquinone, vitamin Q10

 
 
 

Suggested Dosing

50-200 mg PO daily

CHF: 100 mg/day div BID-TID PO

Myocardial preservation for heart surgery: 200 mg/day PO

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Suggested Uses

Angina, chronic fatigue syndrome, CHF, diabetes mellitus, doxorubicin-induced cardiotoxicity (prevention), HIV/AIDS immunostimulant, hypertension, mitochondrial cytopathies, muscular dystrophies, myopathy (statin-induced)

Efficacy may be effective in CHF, MI, mitochondrial encephalomyopathies

Reduces BP; more studies need before recommendation in hypertension

Inconclusive for stable angina, cardiomyopathy, periodontal disease

Huntington's Disease (Orphan)

Orphan indication sponsors

  • Integrative Therapeutics, Inc; 825 Challenger Drive; Green Bay , WI 54311
  • Gel-Tec, Division of Tishcon Corp; 30 New York Avenue; PO Box 331; Westbury, NY 11590

Mitochondrial Cytopathies (Orphan)

Orphan indication sponsor

  • Gel-Tec, Division of TISHCON Corporation; 30 New York Avenue; PO Box 331; Westbury, NY 11590

Pediatric Congestive Heart Failure (Orphan)

Orphan indication sponsor

  • Gel-Tec, Division of TISHCON Corporation; 30 New York Avenue; PO Box 331; Westbury, NY 11590
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Interactions

Interaction Checker

Coenzyme Q10 and

No Results

     
     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Frequency Not Defined

            Diarrhea

            Appetite decreased

            Elevated LFTs

            Gastric distress

            Nausea

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            Warnings

            Cautions

            Biliary obstruction, concurrent antihypertensives, concurrent cancer chemotherapy, concurrent radiation therapy, hepatic insufficiency, hypertension

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            Pregnancy & Lactation

            Pregnancy Category: N/A

            Lactation: N/A

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Pharmacology

            Metabolism: N/A

            Excretion: N/A

            Mechanism of Action

            Ubiquinone: involved in electron transport chain

            Ubiquinol: antioxidant, membrane stabilizer

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