500 mg/d dry extract, no more than 6 g/d
320-640 mg artichoke leaf extract PO TID
1800-1920 mg PO qD div BID-TID (Valverde Artischocke, Novartis Consumer Health)
Appetite loss, liver & gall bladder problems
Efficacy: possibly effective for dyspepsia and hyperlipidemia
Bile duct blockage
Possibility of allergic reactions on frequent contact
Pregnancy & Lactation
Pregnancy Category: N/A
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Mechanism of Action
Cholagogue, contains an active ingredient-Cynarin