cysteamine ophthalmic (Rx)

  • Print
Brand and Other Names:Cystaran

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

ophthalmic solution

  • 0.44%
more...

Corneal Cystine Crystals

Cystine-depleting agent indicated for corneal cystine crystal accumulation in patients with cystinosis

Instill 1 gtt in each eye, every waking hour (ie, q1hr while awake)

Administration

Do not touch dropper tip to any surface to avoid contamination

Keep bottle tightly closed when not in use Discard drops after 1 week of use

Dosage Forms & Strengths

ophthalmic solution

  • 0.44%
more...

Corneal Cystine Crystals

Cystine-depleting agent indicated for corneal cystine crystal accumulation in patients with cystinosis

Instill 1 gtt in each eye, every waking hour (ie, q1hr while awake)

Administration

Do not touch dropper tip to any surface to avoid contamination

Keep bottle tightly closed when not in use Discard drops after 1 week of use

Next:

Adverse Effects

>10%

Light sensitivity

Ocular redness

Eye pain/irritation

Headache

Visual field defects

Previous
Next:

Warnings

Contraindications

None

Cautions

For topical ophthalmic use only

Avoid touching eyelids or surrounding areas with the dropper tip of the bottle to avoid contamination

Benign intracranial hypertension (pseudotumor cerebri) reported with cysteamine PO; there have also been reports associated with cysteamine ophthalmic, however, all of these patients were on concurrent cysteamine PO

Contains benzalkonium chloride, which may be absorbed by soft contact lenses; contact lenses should be removed prior to application and may be reinserted after 15 minutes

Previous
Next:

Pregnancy & Lactation

Pregnancy Category: C

Lactation: Unknown whether distributed in breast milk

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

more...
Previous
Next:

Pharmacology

Mechanism of Action

Acts as a cystine‑depleting agent by converting cystine to cysteine-cysteamine mixed disulfides and reduces corneal cystine crystal accumulation

Absorption

Negligible; incremental increase in systemic cysteamine levels derived from cysteamine ophthalmic applied topically to the eye in patients treated with oral cysteamine was observed to be negligible

Previous
Next:

Images

Previous
Next:

Formulary

FormularyPatient Discounts

Adding plans allows you to compare formulary status to other drugs in the same class.

To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.

Adding plans allows you to:

  • View the formulary and any restrictions for each plan.
  • Manage and view all your plans together – even plans in different states.
  • Compare formulary status to other drugs in the same class.
  • Access your plan list on any device – mobile or desktop.

The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

Tier Description
1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
NC NOT COVERED – Drugs that are not covered by the plan.
Code Definition
PA Prior Authorization
Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
QL Quantity Limits
Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
ST Step Therapy
Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
OR Other Restrictions
Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
Additional Offers
Email to Patient

From:

To:

The recipient will receive more details and instructions to access this offer.

By clicking send, you acknowledge that you have permission to email the recipient with this information.

Email Forms to Patient

From:

To:

The recipient will receive more details and instructions to access this offer.

By clicking send, you acknowledge that you have permission to email the recipient with this information.

Previous