Dosing & Uses
Dosage Forms & Strengths
Acute Alcohol Intoxication
25-50 g (50-100 mL of D50W solution); administer with thiamine (50-100 mg IV) to prevent Wernicke's encephalitis
10-25 g (40-100 mL of D25W solution or 20-50 mL of D50W solution) IV; may require repeated boluses
400-600 mg of glucose/kg/hr needed for most insulin overdoses
Alternatively, administer 25-50 g (D50W) IV; may repeat doses in severe cases; determine glucose levels before injecting dose; in emergencies, may administer promptly before obtaining glucose results
25-50 g (250-500 mL D10W) plus 10 units regular insulin IV over 30-60 min
Serious - Use Alternative
Significant - Monitor Closely
Frequency Not Defined
Possibility of intracellular lactic acid production in setting of ischemic brain cells & hyperglycemia
Extravasation can result in tissue damage
Mechanism of Action
Source of calories and fluid for patients unable to obtain adequate oral intake
Substrate for ATP production for aerobic metabolism; promotes glycogen deposition in the liver
In hyperkalemia dextrose in combination with insulin stimulates the uptake of potassium by cells (especially in muscle tissue), which in turn lowers serum potassium
Onset of action: 10 min (PO; treatement of hypoglycemia)
Absorption: Rapid from the small intestine
Metabolism: Metabolized to carbon dioxide and water
Time to peak: 40 min (PO)
Adding plans allows you to compare formulary status to other drugs in the same class.
To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.
Adding plans allows you to:
- View the formulary and any restrictions for each plan.
- Manage and view all your plans together – even plans in different states.
- Compare formulary status to other drugs in the same class.
- Access your plan list on any device – mobile or desktop.
The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.
|1||This drug is available at the lowest co-pay. Most commonly, these are generic drugs.|
|2||This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.|
|3||This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.|
|4||This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.|
|5||This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.|
|6||This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.|
|NC||NOT COVERED – Drugs that are not covered by the plan.|
Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.