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Fish Oil (Herbs/Suppl)Brand and Other Names:DHA, docosahexaenoic acid (DHA), more...eicosapentaenoic acid (EPA), EPA (fish oils), fish oils, marine oils, menhaden oil, N3 fatty acids, omega 3 PUFA, polyunsaturated fatty acids, PUFA, W3 fatty acids, shark liver oil

 
 
 

Suggested Dosing

Bipolar Disorder, Adjunct Treatment

6.2 g EPA/3.4 g DHA PO daily

Cyclosporine Nephrotoxicity

12 g PO daily

Dysmenorrhea

1080 mg EPA/720 mg DHA PO daily

Hypercholesterolemia

4 g PO daily

Hypertension

4 g PO daily

Hypertriglyceridemia

1-4 g PO daily

See also Omacor

Post CABG

4 g PO daily

Post MI

0.85-1.08 g EPA PO daily

Raynaud's Syndrome

3.96 g EPA/2.64 g DHA PO daily

Rheumatoid Arthritis

3.8 g EPA/2 g DHA PO daily

Sclerosing Cholangitis (Orphan)

Orphan designation for docosahexaenoic acid (DHA) to treat primary sclerosing cholangitis

Sponsor

  • Sancilio and Company, Inc.; 3874 Fiscal Ct, Suite 100; Riviera Beach, FL 33404

Familial Adenomatous Polyposis (Orphan)

Treatment of familial adenomatous polyposis

Orphan indication sponsor

  • S.L.A. Pharma Ltd. (UK); Elite House Leavesden, Watford WD25 7SA; UK

Huntington's Disease (Orphan)

Treatment of familial adenomatous polyposis

Orphan indication sponsor

  • Laxdale Ltd; Kings Park House, Laurelhill Business Park, Polmaise Road, Stirling FK7 9JQ; UK

IgA Nephropathy (Orphan)

Orphan indication sponsor

  • Pronova Biocare, AS; PO Box 420, 1327 Lysaker; Norway

Sickle Cell Disease (Orphan)

Docosahexaenoic acid (DHA)

Orphan designation for treatment of sickle cell disease

Sponsor

  • Sancilio and Company, Inc; 3874 Fiscal Ct., #100; Riviera Beach, FL 33404

Short Bowel Disease (Orphan)

Docosahexaenoic acid (DHA)

Orphan designation for treatment of short bowel disease

Sponsor

  • Sancilio and Company, Inc; 3874 Fiscal Ct., #100; Riviera Beach, FL 33404
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Suggested Uses

Bipolar disorder, coronary heart disease, dysmenorrhea, hyperlipidemia, HTN, hypertriglyceridemia, Raynaud's syndrome, rheumatoid arthritis, stroke prevention

Decr risk of prostate CA (dietary fish)

Rheumatoid arthritis, psoriasis, other chronic inflammatory conditions

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Interactions

Interaction Checker

Fish Oil and

No Results

     
     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Frequency Not Defined

            Bleeding

            Halitosis

            Heartburn

            Hemorrhagic stroke

            Immunosuppression

            Increased LDL cholesterol

            Nausea

            Weight gain

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            Warnings

            Contraindications

            Diabetes, immunodeficiency

            Cautions

            Aspirin sensitivity, bipolar disorder, bleeding disorders, cirrhosis, concurrent antihypertensives, familial adenomatous polyposis, major depressive disorders

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            Pregnancy & Lactation

            Pregnancy Category: N/A

            Lactation: N/A

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Pharmacology

            Metabolism: N/A

            Excretion: N/A

            Mechanism of Action

            Inhibits platelet aggregation; decr production of inflammatory prostaglandins (e.g., PGE2)

            Inhibits oxidation of LDL, inhibits migration of macrophages into atherosclerotic plaques

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