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MSM (Herbs/Suppl)Brand and Other Names:dimethyl sulfone, DMSO2, more...methylsulfonylmethane, Glucosamine & Chondroitin with MSM, Flex-a-min, MSM glucosamine chondroitin, Osteo BiFlex plus MSM, Triflex

 
 
 

Dosing & Uses

AdultPediatric

1000-3000 mg/day, divided, or

400 mg per 50 lbs body weight per day

Take with meals

Other Indications & Uses

Oral and topical: Chronic musculoskeletal & joint pain, scars, wrinkles, periodontal disease, wound healing

Oral: Allergies, depression, peptic ulcer, interstitial cystitis, type 2 DM, lung dysfunction, HIV infection

Efficacy

  • Insufficient information

Safety and efficacy not established

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Adverse Effects

Frequency Not Defined

Nausea

Diarrhea

Headache

Bloating

Fatigue

Insomnia

Difficulty concentrating

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Warnings

Contraindications

Hypersensitivity

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Pregnancy & Lactation

Pregnancy Category: Unknown; avoid use

Lactation: Unknown; avoid use

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

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Pharmacology

Metabolism: N/A

Excretion: N/A

Mechanism of Action

Breakdown product of dimethyl sulfoxide (DMSO); precursor source of sulfur for cysteine and methionine

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