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calcipotriene (Rx)Brand and Other Names:Dovonex, Calcitrene Ointment, more...Sorilux

 
 
 

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

topical solution

  • 0.005%

topical ointment

  • 0.005%

topical cream

  • 0.005%

topical foam

  • 0.005%
more...

Moderate Plaque Psoriasis

Ointment/Cream

  • Apply thin layer to affected skin BID

Solution

  • Apply to affected scalp BID

Foam

  • Apply thin layer topically to affected skin BID

Administration

Rub in gently and completely

May use for up to 8 weeks

Other Information

Foam is flammable, contents under pressure, do not expose to heat or store at temperatures above 120 degrees F

Safety and efficacy not established

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Interactions

Interaction Checker

calcipotriene and

No Results

     
     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            >10%

            Burning

            Itching

            Skin irritation

            1-10%

            Dermatitis

            Dry skin

            Erythema

            Peeling

            Worsening of psoriasis including facial/scalp

            Rash

            <1%

            Folliculitis

            Hypercalcemia

            Hyperpigmentation

            Skin atrophy

            Postmarketing Reports

            Contact dermatitis, including allergic contact dermatitis

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            Warnings

            Contraindications

            Hypersensitivity, use on face, hypercalcemia, or evidence Vit D toxicity

            Cautions

            Photosensitivity reported; avoid excessive exposure to natural or artificial sunlight

            Contact dermatitis, including allergic contact dermatitis, reported

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            Pregnancy & Lactation

            Pregnancy Category: C

            Lactation: excretion in milk unknown; use with caution

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Pharmacology

            Absorption: 5-6% systemically

            Metabolism: converted to inactive metabolites within 24 hr

            Excretion: bile

            Mechanism of Action

            In vitro evidence suggests drug is roughly equipotent to natural vitamin D in its effects on proliferation & differentiation of various cell types

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            Images

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            Formulary

            FormularyPatient Discounts

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            The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

            Tier Description
            1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
            2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
            3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
            4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            NC NOT COVERED – Drugs that are not covered by the plan.
            Code Definition
            PA Prior Authorization
            Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
            QL Quantity Limits
            Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
            ST Step Therapy
            Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
            OR Other Restrictions
            Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
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