travelers diarrhea and cholera vaccine inactivated (Rx)

Brand and Other Names:Dukoral, Mutacol Berna
  • Print

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

Not available in the US

vial vaccine + sachet effervescent granules

more...

Enterotoxigenic E. Coli

Indicated for prevention of travelers' diarrhea caused by enterotoxigenic E coli (ETEC)

Primary immunization: 2 doses PO

Booster: 1 dose PO after 3 months, then q3Months PRN

Cholera

Indicated for prevention of cholera caused by V cholerae in endemic areas (age >2 yr)

Primary immunization: 2 doses PO

Booster: 1 dose PO after 2 years

Dosing Considerations

Not available in the United States

Dosage Forms & Strengths

Not available in the US

vial vaccine + sachet effervescent granules

more...

Enterotoxigenic E. Coli

Indicated for prevention of travelers' diarrhea caused by enterotoxigenic E coli (ETEC)

Primary immunization: 2 doses PO

Booster: 1 dose PO after 3 months, then q3Months PRN

Cholera

Indicated for prevention of cholera caused by V cholerae in endemic areas (age >2 yr)

<2 years: Safety and efficacy not established

Aged 2-6 years

  • Primary immunization: 3 doses PO
  • Booster: 1 dose PO after 6 months

Aged >6 years

  • Primary immunization: 2 doses PO
  • Booster: 1 dose PO after 2 years

Dosing Considerations

Not available in the United States

Next:

Interactions

Interaction Checker

and travelers diarrhea and cholera vaccine inactivated

No Results

     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

            All Interactions Sort By:
             activity indicator 
            Previous
            Next:

            Adverse Effects

            >10%

            Abd pain (16%)

            Previous
            Next:

            Warnings

            Contraindications

            Hypersensitivity to any component

            Acute illness, especially febrile illness

            Parenteral administration

            Cautions

            Immunocompromised persons may not obtain expected immune response

            Travellers should use care in food/water choice, & use good hygiene measures

            Efficacy not studied in pts. >65 yo, but use is recommended

            Not generally recommended for use in pregnancy, but may be considered after risk/benefit analysis (theoretically no risk to fetus)

            Not demonstrated effective against V cholerae O139 Bengal strain in South Asia

            Previous
            Next:

            Pregnancy & Lactation

            Pregnancy Category: N/A

            Lactation: safe for nursing mothers

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

            more...
            Previous
            Next:

            Pharmacology

            Mechanism of Action

            Killed V cholerae and the nontoxic recombinant cholera toxin B subunit

            Antibodies against cholera toxin also confer protection against enterotoxigenic E coli (ETEC)

            Previous
            Next:

            Administration

            Oral Administration

            Mix effervescent granules with 150 mL water, then add vaccine vial

            Administer doses at intervals of 1-6 weeks

            Avoid food 1 hr before and after dosing; separate from oral typhoid vaccine by 8 hr

            Previous
            Next:

            Images

            Previous
            Next:

            Formulary

            FormularyPatient Discounts

            Adding plans allows you to compare formulary status to other drugs in the same class.

            To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.

            Adding plans allows you to:

            • View the formulary and any restrictions for each plan.
            • Manage and view all your plans together – even plans in different states.
            • Compare formulary status to other drugs in the same class.
            • Access your plan list on any device – mobile or desktop.

            The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

            Tier Description
            1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
            2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
            3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
            4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            NC NOT COVERED – Drugs that are not covered by the plan.
            Code Definition
            PA Prior Authorization
            Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
            QL Quantity Limits
            Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
            ST Step Therapy
            Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
            OR Other Restrictions
            Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
            Additional Offers
            Email to Patient

            From:

            To:

            The recipient will receive more details and instructions to access this offer.

            By clicking send, you acknowledge that you have permission to email the recipient with this information.

            Email Forms to Patient

            From:

            To:

            The recipient will receive more details and instructions to access this offer.

            By clicking send, you acknowledge that you have permission to email the recipient with this information.

            Previous