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econazole topical (Rx)Brand and Other Names:Ecoza

 
 
 

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

topical cream

  • 1%

topical foam

  • 1% (Ecoza)
more...

Tinea Fungal Infections & Cutaneous Candidiasis

Indicated for topical application in the treatment of tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Microsporum canis, Microsporum audouini, Microsporum gypseum, and Epidermophyton floccosum; also indicated for treatment of cutaneous candidiasis, and in the treatment of tinea versicolor

Tinea pedis, cruris, corporis, versicolor: Apply cream to affected area(s) qDay

Cutaneous candidiasis: Apply cream to affected area(s) BID

Treatment duration

  • Tinea cruris, corporis, versicolor, cutaneous candidiasis: Apply x 2 weeks
  • Tinea pedis: Apply x4 weeks

Interdigital Tinea Pedis

Indicated for interdigital tinea pedis caused by Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum

Ecoza: Apply foam topically to affected area(s) qDay x4 weeks

Administration

Continue full treatment duration of regimen even after infection clears to complete therapy

Dosage Forms & Strengths

topical cream

  • 1%

topical foam

  • 1% (Ecoza)
more...

Tinea Fungal Infections & Cutaneous Candidiasis

Indicated for topical application in the treatment of tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Trichophyton tonsurans, Microsporum canis, Microsporum audouini, Microsporum gypseum, and Epidermophyton floccosum; also indicated for treatment of cutaneous candidiasis, and in the treatment of tinea versicolor

<3 months: Safety and efficacy not established

Tinea pedis, cruris, corporis, versicolor: Apply cream to affected area(s) qDay

Cutaneous candidiasis: Apply cream to affected area(s) BID

Treatment duration

  • Tinea cruris, corporis, versicolor, cutaneous candidiasis: Apply x 2 weeks
  • Tinea pedis: Apply x4 weeks

Interdigital Tinea Pedis

Indicated for interdigital tinea pedis caused by Trichophyton rubrum, Trichophyton mentagrophytes, and Epidermophyton floccosum

<12 years: Safety and efficacy not established

≥12 years (Ecoza): Apply foam topically to affected area(s) qDay x4 weeks

Administration

Continue full treatment duration of regimen even after infection clears to complete therapy

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Interactions

Interaction Checker

econazole topical and

No Results

     
     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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             activity indicator 
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            Adverse Effects

            1-10%

            Erythema (3%)

            Frequency Not Defined

            Burning and stinging sensations

            Pruritus

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            Warnings

            Contraindications

            Hypersensitivity

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            Pregnancy & Lactation

            Pregnancy Category: C

            Lactation: excretion in milk unknown; use with caution

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Pharmacology

            Mechanism of Action

            Fungistatic in action but may be fungicidal in high concentrations or against very susceptible organisms

            Appears to exert its antifungal and antibacterial activity by altering cellular membranes and interfering with intracellular enzymes

            Pharmacokinetics

            Absorbed: minimal

            Peak Plasma: <1 ng/mL (applied to intact skin); <20 ng/mL (applied to skin stripped of the stratum corneum)

            Excretion: urine & feces (<1%)

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            Images

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            Formulary

            FormularyPatient Discounts

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            The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

            Tier Description
            1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
            2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
            3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
            4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            NC NOT COVERED – Drugs that are not covered by the plan.
            Code Definition
            PA Prior Authorization
            Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
            QL Quantity Limits
            Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
            ST Step Therapy
            Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
            OR Other Restrictions
            Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
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