ferumoxides (Rx)

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Brand and Other Names:Feridex

Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

injectable solution

  • 11.2mg Fe/mL
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Adjunct MRI Enhancement Agent

Used in detection & evaluation of liver lesions associated w/ reticuloendothelial system (RES) alteration

0.56 mg Fe/kg (0.05 mL/kg) in 100 mL D5W IV infusion over 30 min 

Administration

Use vial at room temp

Dilute Feridex IV by injecting it into 100 mL D5W

Use diluted drug within 3 hr

Administer at 2-4 mL/min over 30 min through 5 micron filter

Do NOT administer undiluted

Safety & efficacy not established

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Warnings

Contraindications

Known allergy or hypersensitivity to iron; parenteral dextran, iron-dextran, or iron-polysaccharide preparations

Cautions

Risk of serious, life-threatening, fatal, anaphylactic-like reactions & hypotension

Risk of cardiovascular reactions

Autoimmune disease, iron overload disorder, acute severe back, leg or groin pain

Patients w/ Fe over load disorder (hemosiderosis, chronic hemolytic anemia w/ frequent blood transfusions)

Repeat Procedures: repeat images may be obtained up to 3.5 hrs after original infusion w/out reinjection

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Pregnancy & Lactation

Pregnancy Category: C

Lactation: Excretion in milk unknown/not recommended unless benefits outweigh risks

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

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Formulary

FormularyPatient Discounts

Adding plans allows you to compare formulary status to other drugs in the same class.

To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.

Adding plans allows you to:

  • View the formulary and any restrictions for each plan.
  • Manage and view all your plans together – even plans in different states.
  • Compare formulary status to other drugs in the same class.
  • Access your plan list on any device – mobile or desktop.

The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

Tier Description
1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
NC NOT COVERED – Drugs that are not covered by the plan.
Code Definition
PA Prior Authorization
Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
QL Quantity Limits
Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
ST Step Therapy
Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
OR Other Restrictions
Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
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