Evening Primrose Oil (Herbs/Suppl)

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Brand and Other Names:fever plant, kings cureall, more...night willow herb, oenothera biennis, scabish, stella di sera, sun drop

Suggested Dosing

Eczema, Atopic

4-6 g PO daily

Mastalgia

3-4 g PO daily

Premenstrual Syndrome

2-4 g PO daily

Rheumatoid Arthritis

540 mg-2.8 g PO daily

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Suggested Uses

CAD, eczema (atopic), endometriosis, GI disorders, hypercholesterolemia, intermittent claudication, mastalgia, menopausal symptoms, osteoporosis, premenstrual syndrome, rheumatoid arthritis

Efficacy

Possibly effective for PMS, mastalgia, osteoporosis

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Adverse Effects

Frequency Not Defined

Headache

Indigestion

Nausea

Pregnancy complications

Soft stools

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Warnings

Contraindications

None Reported

Cautions

Bleeding disorders, concomitant anesthesia, schizophrenia, seizure disorder

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Pregnancy & Lactation

Pregnancy Category: X

Lactation: unsafe

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

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Pharmacology

Metabolism: N/A

Excretion: N/A

Mechanism of Action

Gamma-linolenic acid (GLA) metabolized to anti-inflammatory prostaglandins

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