bisacodyl rectal (OTC)

Brand and Other Names:Fleet Bisacodyl Enema, Fleet Bisacodyl Suppository
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

enema

  • 10mg/30mL

suppository

  • 10mg
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Constipation

Enema: Contents of 1 bottle (ie, 37 mL) rectally as a single dose

Suppository: Remove outer wrap and insert 1 suppository into rectum

Enema Administration

Patient should lie on left side with right knee bent

Gently insert enema tip into rectum using slight side-to-side movement; point enema tip toward navel (ease insertion by having patient bear down, as if having a bowel movement, to relax anal muscles)

Do not force enema tip into rectum

Squeeze bottle to deliver appropriate dose

Remove enema tip from rectum

Retain enema in accordance with doctor's instructions

Dosage Forms & Strengths

enema

  • 10mg/30mL

suppository

  • 10mg
more...

Constipation

Enema

  • >12 years: As adults; contents of 1 bottle (ie, 37 mL) rectally as a single dose

Suppository

  • 6-12 years: Remove outer wrap and insert one-half suppository into rectum
  • >12 years: As adults; remove outer wrap and insert 1 suppository into rectum
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Interactions

Interaction Checker

and bisacodyl rectal

No Results

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    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Frequency Not Defined

            Abdominal cramping

            Excessive diarrhea

            Electrolyte and fluid imbalance

            Rectal burning

            Vertigo

            Vomiting

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            Warnings

            Contraindications

            Hypersensitivity

            Obstruction

            Severe impaction

            Symptoms of appendicitis or acute surgical abdomen

            Vomiting

            Rectal bleeding

            Gastroenteritis

            Cautions

            Excessive use may cause electrolyte imbalance, steatorrhea, osteomalacia, diarrhea, & cathartic colon

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            Pregnancy & Lactation

            Pregnancy category: N/A

            Lactation: Excretion in milk unknown

            Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Pharmacology

            Mechanism of Action

            May irritate the colonic intramural plexus of the intestine; alters water and electrolyte secretion, which in turn produces net intestinal fluid accumulation and laxation

            Pharmacokinetics

            Onset of action: 15-60 min

            Half-life: 8 hr (BHPM metabolite)

            Metabolism: Metabolized to BHPM in the colon

            Excretion: Urine (BHPM) and bile

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