sodium phosphate rectal (OTC)

Brand and Other Names:Fleet Enema, Pedia-Lax Enema, more...Fleet Enema Extra
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

Contains mixture of monobasic sodium phosphate and dibasic sodium phosphate

enema

  • (19g/7g)/118mL
  • (19g/7g)/197mL
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Constipation & Bowel Cleansing

Indicated as laxative in the relief of occasional constipation and as part of a bowel cleansing regimen in preparing the colon for surgery, x-ray or endoscopic examination

1 bottle PR; not to exceed 1 administration/24 hr

Administration

Remove orange protective shield from enema tip before inserting; with steady pressure, gently insert enema tip into rectum with a slight side-to-side movement, with tip pointing toward navel

Insertion may be easier if person receiving enema bears down, as if having a bowel movement; this helps relax the muscles around the anus

Do not force enema tip into rectum as this can cause injury

Squeeze bottle until nearly all liquid is gone; it is not necessary to empty the bottle completely, as it contains more liquid than needed

Remove enema tip from rectum and maintain position until urge to evacuate is strong (usually 1-5 minutes)

Do not retain enema solution for more than 10 minutes

Enema should be at room temperature before use

Positions for using this enema

  • Left-side position: Lie on left side with knee bent, and arms resting comfortably
  • Knee-chest position: Kneel, and then lower head and chest forward until left side of face is resting on surface with left arm folded comfortably

Dosage Forms & Strengths

Contains mixture of monobasic sodium phosphate and dibasic sodium phosphate

enema

  • (9.5g/3.5g)/59mL
more...

Constipation & Bowel Cleansing

Indicated as laxative in the relief of occasional constipation and as part of a bowel cleansing regimen in preparing the colon for surgery, x-ray or endoscopic examination

<2 years: Do not use

2-4 years: Administer one-half bottle PR of pediatric enema (ie, ~30 mL); prepare dose by unscrewing cap from bottle and removing 2 tablespoons of liquid (30 mL) with a measuring spoon, replace cap and administer remaining liquid

5-11 years: Administer 1 bottle PR of pediatric enema (ie, 59 mL)

12 years or older: Administer as in adults (adult enema)

Administration

Remove orange protective shield from enema tip before inserting; with steady pressure, gently insert enema tip into rectum with a slight side-to-side movement, with tip pointing toward navel

Insertion may be easier if person receiving enema bears down, as if having a bowel movement; this helps relax the muscles around the anus

Do not force enema tip into rectum as this can cause injury

Squeeze bottle until nearly all liquid is gone; it is not necessary to empty the bottle completely, as it contains more liquid than needed

Remove enema tip from rectum and maintain position until urge to evacuate is strong (usually 1-5 minutes)

Do not retain enema solution for more than 10 minutes

Enema should be at room temperature before use

Positions for using this enema

  • Left-side position: Lie on left side with knee bent, and arms resting comfortably
  • Knee-chest position: Kneel, and then lower head and chest forward until left side of face is resting on surface with left arm folded comfortably
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Interactions

Interaction Checker

and sodium phosphate rectal

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      Serious - Use Alternative

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            Adverse Effects

            Frequency Not Defined

            Hypersensitivity

            Pruritus

            Dehydration

            Hyperphosphatemia

            Hypocalcemia

            Hypokalemia

            Hypernatremia

            Metabolic acidosis

            Nausea

            Vomiting

            Abdominal pain

            Abdominal distension

            Diarrhea

            Gastrointestinal pain

            Chills

            Blistering

            Stinging

            Anal discomfort

            Proctalgia

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            Warnings

            Contraindications

            Hypersensitivity

            Cautions

            Do not use laxatives when nausea, vomiting, or severe abdominal pain is present

            Caution with renal impairment or ascites

            Caution in patients with a colostomy

            Caution in children aged 2-11 years or elderly patients with comorbidities

            Caution if coadministered with medications known to affect renal perfusion, function, or hydration

            Caution with pre-existing electrolyte disturbances or patients taking diuretics or other medications that may alter electrolytes

            Because of risk electrolyte disturbances, caution with medications known to prolong QT interval

            Additional liquids by mouth are recommended to prevent dehydration

            Exceeding daily dose, no return of enema solution, retention time >10 minutes, or failure to have a bowel movement within 30 minutes of enema use may lead to electrolyte disturbances, including hypernatremia, hyperphosphatemia, hypocalcemia, and hypokalemia

            Severe dehydration and electrolyte abnormalities associated with serious complications (eg, acute kidney injury, arrhythmias, and death) have occurred in adults and children who overdosed using oral or rectal over-the-counter (OTC) sodium phosphate solutions to treat constipation

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            Pregnancy & Lactation

            Pregnancy Category: C

            Lactation: Unknown whether distributed in breast milk; caution because of risk for electrolyte disturbances or dehydration

            Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Pharmacology

            Mechanism of Action

            Saline cathartic effect

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            Images

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