Adult Dosing & Uses
Dosing Forms & Strengths
nasal spray
- 27.5mcg/spray
- 50mcg/spray
Seasonal/Perennial Allergic Rhinitis
Flonase
- 2 sprays in each nostril qDay (ie, 200 mcg/day)
- After first few days, patient may reduce dosage to 1 spray in each nostril qDay (ie, 100 mcg/day)
Veramyst
- 2 sprays in each nostril qDay (ie, 110 mcg/day)
Pediatric Dosing & Uses
Dosing Forms & Strengths
nasal spray
- 27.5mcg/spray
- 50mcg/spray
Seasonal/Perennial Allergic Rhinitis
Flonase
- >4 years: 1 spray (50 mcg) in each nostril qDay; may increase up to 2 sprays/nostril qDay
Veramyst
- 2-11 years: 1 spray (27.5 mcg) in each nostril qDay; may increase up to 2 sprays/nostril qDay
- 12 years or older: As adult; 2 sprays/nostril qDay
Adverse Effects
>10%
Headache (17%)
URI (15%)
1-10%
Pharyngitis (10%)
Nasal congestion (8%)
Nasal discharge (5%)
Allergic rhinitis (5%)
Dysphonia (4%)
Frequency Not Defined
Loss of taste
Postmarketing Reports
Respiratory, thoracic, and mediastinal disorders: Rhinalgia, nasal discomfort (including nasal burning, nasal irritation, and nasal soreness), nasal dryness, and nasal septal perforation
Contraindications & Cautions
Contraindications
Hypersensitivity
Recent nasal injury/surgery
Cautions
Respiratory tract TB, untreated fungal or bacterial infections, viral/ parasitic infections, or ocular herpes simplex
Chickenpox and measles: serious or fatal course in susceptible individuals; unvaccinated or immunologically unexposed children or adults should avoid exposure
Local nasal effects, nasal septum perforation, epistaxis, wheezing, cataracts, glaucoma
Pregnancy & Lactation
Pregnancy Category: C
Lactation: Unknown whether distributed in breast milk; caution advised
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Pharmacology
Mechanism of Action
Anti-inflammatory corticosteroid

