fluticasone intranasal (Rx) - Flonase, Veramyst

 
 
 

Adult Dosing & Uses

Dosing Forms & Strengths

nasal spray

  • 27.5mcg/spray
  • 50mcg/spray

Seasonal/Perennial Allergic Rhinitis

Flonase

  • 2 sprays in each nostril qDay (ie, 200 mcg/day)
  • After first few days, patient may reduce dosage to 1 spray in each nostril qDay (ie, 100 mcg/day)

Veramyst

  • 2 sprays in each nostril qDay (ie, 110 mcg/day)
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Pediatric Dosing & Uses

Dosing Forms & Strengths

nasal spray

  • 27.5mcg/spray
  • 50mcg/spray

Seasonal/Perennial Allergic Rhinitis

Flonase

  • >4 years: 1 spray (50 mcg) in each nostril qDay; may increase up to 2 sprays/nostril qDay

Veramyst

  • 2-11 years: 1 spray (27.5 mcg) in each nostril qDay; may increase up to 2 sprays/nostril qDay
  • 12 years or older: As adult; 2 sprays/nostril qDay
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Adverse Effects

>10%

Headache (17%)

URI (15%)

1-10%

Pharyngitis (10%)

Nasal congestion (8%)

Nasal discharge (5%)

Allergic rhinitis (5%)

Dysphonia (4%)

Frequency Not Defined

Loss of taste

Postmarketing Reports

Respiratory, thoracic, and mediastinal disorders: Rhinalgia, nasal discomfort (including nasal burning, nasal irritation, and nasal soreness), nasal dryness, and nasal septal perforation

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Contraindications & Cautions

Contraindications

Hypersensitivity

Recent nasal injury/surgery

Cautions

Respiratory tract TB, untreated fungal or bacterial infections, viral/ parasitic infections, or ocular herpes simplex

Chickenpox and measles: serious or fatal course in susceptible individuals; unvaccinated or immunologically unexposed children or adults should avoid exposure

Local nasal effects, nasal septum perforation, epistaxis, wheezing, cataracts, glaucoma

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View Category Definitions

Pregnancy & Lactation

Pregnancy Category: C

Lactation: Unknown whether distributed in breast milk; caution advised

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

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Pharmacology

Mechanism of Action

Anti-inflammatory corticosteroid

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Pricing & Images

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