Dosing & Uses
Dosage Forms & Strengths
Provides topical ophthalmic anesthesia with a disclosing agent for short corneal and conjunctival procedures
1 drop in each eye q 5-10 minutes x5-7 doses
Use of an eye patch is recommended
Safety and efficacy not established
Frequency Not Defined
Transient local stinging
Transient local burning
Severe, immediate allergic corneal reaction (rare)
Allergic contact dermatitis (rare)
Conjunctival congestion (rare)
Conjunctival hemorrhage (rare)
Hypersensitivity to either component or to similar drugs
Prolonged use not recommended as may diminish duration of anesthesia, retard wound healing, and cause corneal infection and/or opacification with accompanying permanent visual loss or corneal perforation
Systemic toxicity (CNS stimulation followed by CNS and cardiovascular depression) possible but rare
Protection of the eye from other irritating chemicals, foreign bodies, and rubbing during the period of anesthesia is very important
Use cautiously and sparingly in patients with known allergies, cardiac disease, or hyperthyroidism
Pregnancy & Lactation
Pregnancy Category: C Administer in pregnancy only if clearly needed
Lactation: Unknown whether distributed in breast milk, caution advised
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Onset: 30 sec
Duration: 10-20 min
Mechanism of Action
Fluorescein sodium: contact with aqueous humor increases intensity of green fluorescence
Proparacaine hydrochloride: topical anesthetics stabilize neuronal membrane so neuron is less permeable to ions, preventing initiation and transmission of nerve impulses, producing local anesthetic action
Adding plans allows you to compare formulary status to other drugs in the same class.
To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.
Adding plans allows you to:
- View the formulary and any restrictions for each plan.
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The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.
|1||This drug is available at the lowest co-pay. Most commonly, these are generic drugs.|
|2||This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.|
|3||This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.|
|4||This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.|
|5||This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.|
|6||This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.|
|NC||NOT COVERED – Drugs that are not covered by the plan.|
Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.