folic acid/cyanocobalamin/pyridoxine (Rx)

Brand and Other Names:Foltx, folic acid/vitamin B12/vitamin B6, more...Folbic
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

folic acid/cyanocobalamin/pyridoxine

tablet

  • 0.4mg/250mg/25mg
  • 0.8mg/100mcg/50mg
  • 0.8mg/1000mcg/50mg
  • 0.8mg/115mcg/10mg
  • 0.8mg/250mcg/25mg
  • 0.8mg/400mcg/25mg
  • 2.2mg/500mcg/25mg
  • 2.2mg/1000mcg/25mg
  • 2.2mg/1300mcg/25mg
  • 2.5mg/2000mcg/25mg
  • 2.5mg/1000mcg/25mg
more...

Daily Dietary Supplement

1 tab PO qDay

Safety & efficacy not established

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Interactions

Interaction Checker

and folic acid/cyanocobalamin/pyridoxine

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    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Frequency Not Defined

            Allergic reactions

            Bronchospasm

            Flushing

            Malaise

            Erythema

            Rash

            Paresthesias

            Somnolence

            Unsteady gait

            Diarrhea

            Nausea

            Pruritus

            Urticaria

            Altered sleep patterns

            Irritability

            Peripheral vascular thrombosis

            Polycythemia

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            Warnings

            Contraindications

            Hypersensitivity to any component

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            Pregnancy & Lactation

            Pregnancy Category: See individual agents

            Lactation: Safe

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Nutrition

            See individual monographs

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            Pharmacology

            Mechanism of Action

            Folic acid: Plays a role in the formation of coenzymes involved in purine and pyrimidine synthesis as well as other metabolic systems; required for nucleoprotein synthesis and maintenance of erythropoiesis; enhances metabolism of formic acid, the toxic metabolite of methanol, to nontoxic metabolites

            Cyanocobalamin: Plays a role in cell replication and hematopoiesis; coenzyme in protein synthesis as well as fat and carbohydrate metabolism

            Pyridoxine: Plays a role in carbohydrate, protein, and fat metabolism; aids in the release of liver and muscle stored glycogen and the synthesis of GABA

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            Images

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            Formulary

            FormularyPatient Discounts

            Adding plans allows you to compare formulary status to other drugs in the same class.

            To view formulary information first create a list of plans. Your list will be saved and can be edited at any time.

            Adding plans allows you to:

            • View the formulary and any restrictions for each plan.
            • Manage and view all your plans together – even plans in different states.
            • Compare formulary status to other drugs in the same class.
            • Access your plan list on any device – mobile or desktop.

            The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

            Tier Description
            1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
            2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
            3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
            4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
            NC NOT COVERED – Drugs that are not covered by the plan.
            Code Definition
            PA Prior Authorization
            Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
            QL Quantity Limits
            Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
            ST Step Therapy
            Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
            OR Other Restrictions
            Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
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