neomycin/polymyxin B/gramicidin ophthalmic (Rx)

Brand and Other Names:Gramicidin, Neosporin Ophthalmic Solution, more...Neocin-PG
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Dosing & Uses

AdultPediatric

Dosage Forms & Strengths

Neomycin/Polymyxin B/Gramicidin

ophthalmic solution

  • (1.75 mg/10,000/0.025 mg)/1mL (10mL)
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Treatment & Prevention of Ocular Infection &/or Inflammation

1-2 gtts q4-6hr for 7-10 days; if severe 2 gtts q1hr if necessary

Dosage Forms & Strengths

Neomycin/Polymyxin B/Gramicidin

ophthalmic solution

  • (1.75 mg/10,000/0.025 mg)/1mL (10mL)
more...

Treatment & Prevention of Ocular Infection &/or Inflammation

1-2 gtts q4-6hr for 7-10 days; if severe 2 gtts q1hr if necessary

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Adverse Effects

Frequency Not Defined

Hypersensitivity

Itching, swelling, and conjunctival erythema

Local transient irritation

Vesicular and maculopapular dermatitis

Angioneurotic edema

Urticaria

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Warnings

Contraindications

Aminglycoside/neomycin hypersensitivity; hypersensitivity to any product component

Cautions

Watch for NEOMYCIN ocular sensitivity

Defects in visual acuity may occur with prolonged use

Posterior subpapular cataract formation, and secondary ocular infections reported with prolonged use

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Pregnancy & Lactation

Pregnancy Category: C

Lactation: Excretion in breast milk unknown; use caution

Pregnancy Categories

A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

NA:Information not available.

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Pharmacology

Mechanism of Action

Inhibits bacterial cell wall synthesis by preventing the incorporation of amino acids and nucleotides into the cell wall

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Formulary

FormularyPatient Discounts

Adding plans allows you to compare formulary status to other drugs in the same class.

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  • View the formulary and any restrictions for each plan.
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The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information.

Tier Description
1 This drug is available at the lowest co-pay. Most commonly, these are generic drugs.
2 This drug is available at a middle level co-pay. Most commonly, these are "preferred" (on formulary) brand drugs.
3 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs.
4 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
5 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
6 This drug is available at a higher level co-pay. Most commonly, these are "non-preferred" brand drugs or specialty prescription products.
NC NOT COVERED – Drugs that are not covered by the plan.
Code Definition
PA Prior Authorization
Drugs that require prior authorization. This restriction requires that specific clinical criteria be met prior to the approval of the prescription.
QL Quantity Limits
Drugs that have quantity limits associated with each prescription. This restriction typically limits the quantity of the drug that will be covered.
ST Step Therapy
Drugs that have step therapy associated with each prescription. This restriction typically requires that certain criteria be met prior to approval for the prescription.
OR Other Restrictions
Drugs that have restrictions other than prior authorization, quantity limits, and step therapy associated with each prescription.
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