Medicinal mushroom extract (liquid, tablet, capsule) 3-7.0 g/d PO
Maitake mushrooms: may be consumed as food or made into tea
Treatment or prevention of cancer
Boosts human immune system & limits or reverses tumor growth
Enhances benefits of chemo & lessens side effects of hair loss, pain, & nausea
Clinical trials currently undergoing study:
to learn if beta glucan can increase effectiveness of rituximab by making cancer cells more sensitive to it
of young patients with relapsed or progressive lymphoma, leukemia, or similar d/o
with other drugs to learn if they increase effectiveness of another monoclonal antibody
for breast cancer treatment; neuroblastoma patients that have not responded to treatment
combining different types of biological treatment
Serious - Use Alternative
Significant - Monitor Closely
Commercial preparations may vary in strength, check Mfr's label
Pregnancy & Lactation
Pregnancy Category: check with physician
Lactation: check with physician
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Mechanism of Action
Maitake D-fraction contains a polysaccharide called beta-glucan believed to stimulate & activate certain immune cells & proteins that attack cancer cells: macrophages, T-cellls, natural killer cells, & interleukin 1 & 2
- Current clinical trials undergoing study