Follow Mfr's instructions
General Dosing Guidelines
300-500 mg PO BID/TID
Extract: 333 mg TID PO
Extract: 3600 mg/day
Gum Resin preparation: 350 mg TID PO
300 mg TID PO
Generally 300-500 mg PO BID/TID, higher in IBD
Osteoarthritis, rheumatoid arthritis, asthma, inflammatory bowel disease, diuretic, painful menstration
Clinical trials have shown beneficial evidence for all of the above uses but of varying consistency & reliability
Frequency Not Defined
May be emmenagogue & abortificient
Pregnancy & Lactation
Pregnancy Category: avoid
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Mechanism of Action
Boswellic acid, the major constituent is thought to contain pharmacologic potency
Inhibits 5-lipoxygenase in vitro & in animal studies