iodine (OTC)

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Brand and Other Names:

Dosing & Uses

AdultPediatric

RDA

150 mcg/day

Pregnancy: 220 mcg/day

Lactation: 290 mcg/day

RDA

1-8 years: 90 mcg/day

8-13 years: 120 mcg/day

13-18 years: 150 mcg/day

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Interactions

Interaction Checker

and iodine

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    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Frequency Not Defined

            Metallic taste

            Fever

            Arthralgia

            Diarrhea

            Angioedema

            Urticaria

            Eosinophilia

            Headache

            Pulmonary edema

            Thyroid suppression

            Acne (high dose)

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            Warnings

            Contraindications

            Hypersensitivity to drug or components

            Cautions

            Excessive iodine may cause hypothyroidism by feedback inhibition of thyroid hormone production & conversion of triiodothyronine (T3) to less active thyroxine (T4)

            Use caution in patients with renal impairment

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            Pregnancy & Lactation

            Pregnancy Category: Not studied

            Lactation: Enters breast milk; use caution

            Pregnancy Categories

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Pharmacology

            Mechanism of Action

            Required for thyroid hormone synthesis; component of thyroid hormones (T3 & T4)

            Pharmacokinetics

            Bioavailability: 90%

            Excretion: 90% (urine)

            Distribution: Thyroid

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