poliovirus vaccine inactivated (Rx) - IPOL, IPV, more..Poliovax

 
 
 

Adult Dosing & Uses

Poliovirus Prevention

Routine vaccination not recommended for adults (18 years or older) residing in the US; however, unimmunized or incompletely immunized adults exposed to wild poliovirus should be vaccinated with a 3-dose series

0.5 mL SC/IM 2 doses 1-2 months apart with 3rd dose 6-12 months later, OR

3 doses >1 months apart or enough to complete total 3 doses

Completely vaccinated adults can receive 1 booster dose if traveling to polio endemic areas or to areas where the risk of exposure is high

Risk of exposure to wild polioviruses

  • Travelers to regions or countries where poliomyelitis is endemic or epidemic
  • Healthcare workers in close contact with patients who may be excreting polioviruses
  • Laboratory workers handling specimens that may contain polioviruses
  • Members of communities or specific population groups with disease caused by wild polioviruses

Additional Information

Up-to-date vaccination schedules available at www.cdc.gov/nip/publications

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Pediatric Dosing & Uses

Poliovirus Prevention

<6 weeks old: Safety/efficacy not established

0.5 mL SC/IM; 2 doses 1-2 months apart (at 2 and 4 months old), 3rd dose 18 months later; and fourth dose at age 4-6 years old before entering school

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Drug Interactions

Interaction Checker

poliovirus vaccine inactivated and

No Results

     
     activity indicator 
    No Interactions Found
    Interactions Found

    Contraindicated

      Serious - Use Alternative

        Significant - Monitor Closely

          Minor

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            Adverse Effects

            Suspected adverse events after administration of any vaccine may be reported to Vaccine Adverse Events Reporting System (VAERS), 1-800-822-7967

            >10%

            Irritability (7-65%)

            Tiredness (4-61%)

            Fever >39 degrees C (38%)

            Injection site tenderness (29%)

            Injection site pain (13%)

            Injection site swelling (11%)

            1-10%

            Erythema at inj site (3%), induration (1%)

            Vomiting (1-3%)

            Crying (1%)

            Postmarketing Reports

            Guillain-Barre syndrome

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            Contraindications & Cautions

            Contraindications

            Hypersensitivity to neomycin, streptomycin, polymixin B

            Defer if acute febrile illness

            Concomitant methotrexate

            Cautions

            Do not administer additional doses if anaphylaxis to previous dose

            Immunosuppressed pts may not develop immunity

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            View Category Definitions

            Pregnancy & Lactation

            Pregnancy Category: C

            Lactation: not known if excreted in breast milk

            A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.

            B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.

            C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.

            D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.

            X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.

            NA:Information not available.

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            Pharmacology

            Mechanism of Action

            Inactivated virus of 3 strains; elicits antibody response following immunization

            These products convey active immunity via stimulation of production of endogenously produced antibodies

            The onset of protection from disease is relatively slow, but duration is long lasting (years)

            Duration: Not established

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            Pricing & Images

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