Brand and Other Names:Iquix, Quixin
- Classes: Quinolones, Ophthalmic
Dosing & Uses
Dosage Forms & Strengths
1-2 gtt in affected eye(s) q2hr on days 1-2, while awake, up to 8 times/day, THEN
1-2 gtt q4hr; not to exceed four times daily on days 3-7
Dosage Forms & Strengths
Ophth soln 0.5%
<1 year: Safety & efficacy not established
1 year or older: 1-2 gtt in affected eye(s) q2hr on days 1-2, while awake, up to 8 times/day, THEN 1-2 gtt q4hr; not to exceed QID on days 3-7
Frequency Not Defined
Transient decrease in vision
Transient ocular burning
Ocular pain or discomfort
Foreign body sensation
Hypersensitivity to quinolones or any component
May result in overgrowth of nonsusceptible organisms, including fungi
Some pts may require slit-lamp biomicroscopy & fluorescein staining
serious hypersensitivity reactions with systemic use of fluoroquinolones reported; use caution
Safety and efficacy on children
Pregnancy & Lactation
Pregnancy Category: C
Lactation: May be distributed into milk; use caution
A:Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B:May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C:Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D:Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X:Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
NA:Information not available.
Mechanism of Action
Inhibits DNA topoisomerase (ATP-hydrolyzing), a type II DNA topoisomerase commonly referred to as DNA-gyrase, in susceptible organisms; promotes breakage of DNA strands, inhibits relaxation of supercoiled DNA; inhibits DNA repair and recombination
Absorption: Minimal with ophthalmic use
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|1||This drug is available at the lowest co-pay. Most commonly, these are generic drugs.|
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